Anesthesia for thoracoscopic surgery
Conditions
Interventions
Control group:After the patient enters the operating room, vital signs are monitored, and peripheral venous access is established. There are no specific requirements for muscle relaxants in the anesth
Experimental Group 1:After the patient enters the operating room, vital signs are monitored. The patient is instructed to lie on their side, and under ultrasound guidance, serratus anterior block is p
Experimental Group 2:After the patient was admitted to the operating room, vital signs were monitored, the patient was instructed to lie on the side, and ultrasound-guided anterior serratus block was
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Age =18 years and =80 years, any gender; 2.Patients undergoing thoracoscopic lung resection surgery; 3.ASA classification of grade I or II; 4.Clearly understand and voluntarily participate in the study, with informed consent signed by themselves or their family members.
Exclusion criteria
Exclusion criteria: 1.Surgery time =3 hours; 2.Severe heart diseases such as serious arrhythmia, heart failure, Adams-Stokes syndrome, unstable angina, myocardial infarction within the past 6 months, history of tachycardia/bradycardia requiring medication, third-degree atrioventricular block, or QTcF interval =450ms (corrected by Fridericia’s formula), or exercise tolerance <4 METs; 3.Systolic blood pressure =180 mmHg and/or diastolic pressure =110 mmHg measured upon entering the operating room; 4.Respiratory insufficiency, history of severe obstructive or restrictive lung diseases, bronchospasm requiring treatment within the past 3 months, acute respiratory infection within the past week with symptoms such as significant fever, wheezing, nasal congestion, and cough; 5.Uncontrolled clinically significant diseases of the liver, kidneys, blood, nervous system, or metabolic disorders that may be deemed unsuitable for study participation by the researcher; 6.Pregnant or breastfeeding women; 7.Known allergy to opioids, local anesthetics, or other anesthetic drugs; 8.Participation in another clinical drug trial within the past 3 months; 9.History of cranial injury, potential seizures, myoclonus, intracranial hypertension, cerebral aneurysm, cerebrovascular accident, schizophrenia, intellectual disability, mania, psychosis, long-term use of psychiatric medication, drug addiction, or cognitive dysfunction; 10.Patients deemed unsuitable for the trial by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anesthesia-related adverse events within 48 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative opioid dosage;Postoperative patient pain scores;Opioid analgesic use in postoperative patients;Postoperative patient satisfaction with analgesia; | — |
Countries
China
Contacts
Public ContactZhang Li
Zhongshan Hospital, Fudan University
Outcome results
None listed