postoperative cognitive dysfunction
Conditions
Interventions
Observation group:NONE
Sponsors
Xuzhou No 1 People’s Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiology (ASA) physical status classification I to III. 2. Age between 65 and 80 years old. 3. No gender restrictions. 4. Women of childbearing age must be non-pregnant. 5. The subject or their legally authorized representative has signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with heart function class III or above; 2. Patients with vital capacity (VC) or forced expiratory volume in one second (FEV1) less than 50% of the predicted value; 3. Patients with severe dehydration and severe malnutrition; 4. Patients with preoperative biochemical tests indicating liver and kidney dysfunction; 5. Patients with neurological or psychiatric disorders, or severe systemic diseases; 6. Patients who have been using sedatives or psychiatric medications long-term or recently; 7. Patients with a mini-mental state examination (MMSE) score of less than 23 points or who are unable to complete the learning plan or operations as required; 8. Patients with visual, auditory, or language communication disabilities; 9. Patients who are unwilling to comply with or cooperate with cognitive function testing; 10. Patients with alcohol abuse or drug addiction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Simple Intelligent Mental State Examination Scale;Hopkins Verbal Learning Test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Symbol Digit Modalities Test; | — |
Countries
china
Contacts
Public ContactYANG Li
Xuzhou No 1 People’s Hospital
Outcome results
None listed