Sepsis-Associated Encephalopathy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age = 18 years old; (2) All septic patients who meet the sepsis 3.0 diagnostic criteria; (3) The patient or their family must sign the informed consent form for study enrollment. Note: The diagnostic criteria for sepsis according to the "International Consensus on Definitions for Sepsis and Septic Shock, Third Edition (sepsis-3)" are: suspected or documented infection; a SOFA score increase of =2 points from baseline. Using the CAM-ICU to assess the patient's mental status twice daily, all patients in the ICU are categorized into the SAE group and the non-neurologic septic group based on CAM-ICU results. Patients are placed in the SAE group if they experience acute changes or fluctuations in consciousness, attention deficits, altered levels of consciousness, or confusion
Exclusion criteria
Exclusion criteria: (1) Time in ICU < 24 hours; (2) Age < 18 years; (3) After cardiac and respiratory resuscitation, brain injury, primary central nervous system diseases (stroke, intracranial infection, intracranial mass), metabolic encephalopathy, arrhythmia, intra-aortic balloon pump (IABP), extracorporeal membrane oxygenation (ECMO); (4) Consciousness impairment existed before transferring to ICU; (5) Severe visual or hearing impairment; (6) Chronic kidney dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Septic encephalopathy ; | — |
Countries
China
Contacts
The second hospital of hebei medical university