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The application research of heparin-binding protein combined with procalcitonin (HBP/PCT) in acute infectious diseases.

The application research of heparin-binding protein combined with procalcitonin (HBP/PCT) in acute infectious diseases.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400090479
Enrollment
Unknown
Registered
2024-09-30
Start date
2024-09-30
Completion date
Unknown
Last updated
2024-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

Gold Standard:SOFA score
Index test:Heparin-binding protein (HBP)

Sponsors

Beijing hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age = 18 years old; 2. Presenting to the emergency department with suspected acute infectious disease, with the attending physician preliminarily determining whether it is considered an acute infectious disease based on the patient's relevant symptoms and signs (new or worsening cough, sputum production, frequent urination, urgency, dysuria, abdominal pain, diarrhea, etc.), fever, and auxiliary examination results; 3. Voluntarily participating in this study after signing the informed consent form.

Exclusion criteria

Exclusion criteria: 1. End-stage disease, including advanced cancer, with patients expected to die within 72 hours; 2. A diagnosis of sepsis has been clearly established at an outside hospital for more than 48 hours; 3. The patient or family refuses to participate in this study; 4. Patients who are transferred to another hospital for continued treatment within 24 hours; 5. Patients who are pregnant; 6. Patients who are unable to complete follow-up.

Design outcomes

Primary

MeasureTime frame
sensitivity;specificity;Positive Predictive Value;28-day mortality prediction sensitivity;

Countries

China

Contacts

Public ContactQuan jinhua/Zhang xinchao

Beijing hospital

quan_jinhua2014@163.com+86 159 1082 8260

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026