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Construction and validation of a risk prediction model for cardiotoxicity related to cancer treatment in breast cancer patients undergoing chemotherapy

Construction and validation of a risk prediction model for cardiotoxicity related to cancer treatment in breast cancer patients undergoing chemotherapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400090456
Enrollment
Unknown
Registered
2024-09-30
Start date
2024-10-07
Completion date
Unknown
Last updated
2024-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

Observation group:None

Sponsors

Sun Yat-sen University, school of nursing
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Pathological diagnosis of early breast cancer (TNM stage I-III); (2) Age =18 years old; (3) No previous history of chemotherapy, radiotherapy or targeted therapy; (4) Chemotherapy regiments containing anthracyclines (combined with or without targeted drug therapy) are proposed; (5) Voluntarily cooperate, and expect to participate in the full cycle of the study and sign a written informed consent.

Exclusion criteria

Exclusion criteria: (1) Previous history of malignant tumor; (2) Before the diagnosis of breast cancer, serious cardiovascular events such as acute heart failure, acute myocardial infarction, acute cerebral hemorrhage, severe valvular disease, malignant arrhythmia, NYHA grade IV occurred; (3) Complicated with heart, liver, lung, kidney and other serious organic injury diseases; (4) Are receiving psychotherapy or taking psychotropic drugs such as antidepressants.

Design outcomes

Primary

MeasureTime frame
Related indicators of cardiac function;

Secondary

MeasureTime frame
Laboratory examination of relevant indicators;

Countries

China

Contacts

Public ContactLiu Ting

Sun Yat-sen University, school of nursing

liut333@mail.sysu.edu.cn+86 199 0227 9414

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026