Postoperative Delirium
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients undergoing hip or knee replacement under general anaesthesia 2. Aged >=65 years 3. ASA I~III 4. Expected survival > 12 months 5. Subjects who have signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with serious heart, lung, liver or kidney insufficiency; 2. Patients with serious visual and auditory dysfunction or communication difficulties; 3. Patients who are illiterate or have a low level of education and are unable to complete the scales; 4. Patients with cognitive impairment assessed by Mini-Mental State Examination (MMSE) or a history of dementia, neurological or psychiatric disorders due to a variety of causes; 5. Alcohol or substance abusers;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Delirium;complement 3;complement 4;complement 1q;MMSE;MDAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| educational attainment;age;BMI;Duration of anaesthesia;complication; | — |
Countries
China
Contacts
Affiliated Drum Tower Hospital, Medical School of Nanjing University