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Relationship between plasma complement levels and postoperative delirium in the elderly: a single-centre, prospective, observational cross-sectional research

Relationship between plasma complement levels and postoperative delirium in the elderly: a single-centre, prospective, observational cross-sectional research

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400090451
Enrollment
Unknown
Registered
2024-09-30
Start date
2024-03-24
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Delirium

Interventions

Sponsors

Affiliated Drum Tower Hospital, Medical School of Nanjing University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing hip or knee replacement under general anaesthesia 2. Aged >=65 years 3. ASA I~III 4. Expected survival > 12 months 5. Subjects who have signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with serious heart, lung, liver or kidney insufficiency; 2. Patients with serious visual and auditory dysfunction or communication difficulties; 3. Patients who are illiterate or have a low level of education and are unable to complete the scales; 4. Patients with cognitive impairment assessed by Mini-Mental State Examination (MMSE) or a history of dementia, neurological or psychiatric disorders due to a variety of causes; 5. Alcohol or substance abusers;

Design outcomes

Primary

MeasureTime frame
Postoperative Delirium;complement 3;complement 4;complement 1q;MMSE;MDAS;

Secondary

MeasureTime frame
educational attainment;age;BMI;Duration of anaesthesia;complication;

Countries

China

Contacts

Public ContactGu xiaoping

Affiliated Drum Tower Hospital, Medical School of Nanjing University

xiaopinggu@nju.edu.cn+86 138 1399 6903

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026