Effects of time interval between oocyte retrieval and ICSI on embryo development dynamics and embryo development outcomes - a prospective controlled clinical study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400090437

Enrollment

Unknown

Registered

2024-09-30

Start date

2024-09-30

Completion date

Unknown

Last updated

2024-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reproductive medicine

Interventions

Group A:The OPU-ICSI interval is 2 to 3.5 hours

Group B:OPU-ICSI Time interval Interval > 4 h

Eligibility

Sex/Gender

All

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1) Couples indicated by ICSI, the female is between 20 and 40 years old, and the BMI is in the range of 18-30kg/m2; 2) Infertile women undergoing the first or second cycle of ICSI-ET treatment; 3) Routine controlled ovarian stimulation regimen; Such as antagonist regimen, agonist regimen, or luteal phase ovulation regimen; 4) The number of oocyte obtained is =10; 5) Normal fertilized embryos continue to be cultured in time-lapse; 6) Fully understand the study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1) Patients without ICSI indications; 2) Azoospermia patients and frozen semen cycle; 3) no ovulation cycle;

Design outcomes

Primary

Measure	Time frame
2PN rate;good quality embryo rate;Good blastocyst rate;	—

Countries

China

Contacts

Public ContactHuakun Zhang

Shenzhen Maternity and Child Healthcare Hospital

Kunkun21cen@163.com+86 159 8987 1367

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026