Coronary Heart Disease
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Case Group (Patients with Coronary Heart Disease): Patients diagnosed with coronary heart disease, with diagnostic criteria including but not limited to clinical symptoms, electrocardiogram changes, and coronary angiography. Aged between 18 and 75 years. Possess good self-care abilities and communication skills. Willing to participate in the study and have signed informed consent. Control Group (Healthy Volunteers): Aged between 18 and 75 years. Free from coronary heart disease and other major health conditions, confirmed to be in good health through medical examination and health assessment. Possess good self-care abilities and communication skills. Willing to participate in the study and have signed informed consent.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for Case Group: 1.Presence of other severe systemic diseases within the past six months (e.g., cancer, severe infections). 2.Suffering from severe chronic diseases or complications (e.g., end-stage renal disease, liver failure). 3.Pregnant or breastfeeding women. 4.Recent (within six months) cardiac surgery or other major medical interventions that may affect gene expression. 5.Inability to comply with the study protocol or failure to provide valid samples.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expression Levels of Tryptophan Metabolism-Related Genes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation Between Gene Expression and Clinical Parameters;Gene Co-Expression Analysis;Inter-Individual Variability in Gene Expression; | — |
Countries
China
Contacts
Public ContactHuang Ying
The First Affiliated Hospital of Soochow University
Outcome results
None listed