Coronary heart disease or cerebral infarction
Conditions
Interventions
Patients with atherosclerotic cardiovascular and cerebrovascular diseases:NA
Sponsors
the First Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-80 years old; (2) Patients diagnosed with coronary heart disease (coronary angiography or CTA report) or ischemic cerebral infarction (transcranial Doppler ultrasonography or CT or MRI report) by imaging; (3) Patients with hypercholesterolemia (higher than the target value defined in the 2023 Chinese Adult Lipid Prevention Guidelines); (4) Receiving atherogenic drugs; (5) Patients with probucol tablets; (6) Sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Complicated with severe liver and renal insufficiency, hematological diseases and malignant tumors (discretion belongs to the investigator); (2) Unwilling to attend or unable to cooperate with the accompanying visitors; (3) Patients who are pregnant, breastfeeding or have pregnancy plans and may be pregnant; (4) Patients who are allergic to statins and probucol tablets, or who have had serious adverse reactions after taking statins or probucol tablets in the past; (5) People with prolonged Q-T interval are taking drugs that prolong Q-T interval; (6) Other situations that the researcher considers unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate of ischemic stroke;Incidence of unstable angina pectoris;Incidence of myocardial infarction;Incidence of unstable angina pectoris;Incidence of myocardial infarction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of major adverse cardiovascular events;Incidence of revascularization;Readmission incidence;Incidence of major adverse cardiovascular events;Incidence of revascularization;Readmission incidence; | — |
Countries
China
Contacts
Public ContactYihua Shen
Department of gerontology, the First Affiliated Hospital of Fujian Medical University
Outcome results
None listed