perioperative neurocognitive disorder
Conditions
Interventions
Disease group:None
Control group:None
Sponsors
Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University)
Eligibility
Sex/Gender
All
Age
65 Years to 90 Years
Inclusion criteria
Inclusion criteria: Age 65-90 years old; ASA Level I-III; Patients undergoing non-craniocerebral surgery; The patient or family member can provide written informed consent.
Exclusion criteria
Exclusion criteria: Communication barriers; The disease is in the terminal stage, and is complicated with malignant tumors, serious organ failure, etc. Patients with dementia and severe mental illness; BMI=30; A history of drug abuse; Receiving anti-bacterial/viral treatment; Acute or ongoing infection; Systemic inflammatory diseases; Hypersensitive state; Blood transfusion; Hematologic tumors; Decompensated cardiovascular and cerebrovascular diseases; Data is missing; Those who refuse to cooperate and ask to quit.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peripheral inflammation index (NLR, PLR, MLR, NLPR, SII, AISI);Peripheral immune cell subsets (lymphatic and myeloid);Peripheral immune inflammatory factors;Perioperative neurocognitive function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain;Blood pressure;Heart rate;SpO2;Dizziness;Vomiting;Nausea; | — |
Countries
China
Contacts
Public ContactTan Siyou
Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University)
Outcome results
None listed