Myocardial Infarction
Conditions
Interventions
Decoction Group:In addition to standard treatment for myocardial infarction, administer the Huoxue Huatan decoction: 10g Guawu Pi (Trichosanthes Kirilowii Maxim), 15g Xie Bai (Allium macrostemon Bunge
Low-Dose Granule Group:In addition to standard treatment for myocardial infarction, administer low-dose Huoxue Huatan formula granules, with the same herbal composition as the decoction group of Huoxu
Medium-Dose Granule Group:In addition to standard treatment for myocardial infarction, administer medium-dose Huoxue Huatan formula granules, with the same herbal composition as the decoction group of
High-Dose Granule Group:In addition to standard treatment for myocardial infarction, administer high-dose Huoxue Huatan formula granules, with the same herbal composition as the decoction group of Huo
Sponsors
Guangdong Provincial Hospital of Chinese Medicine (Main Hospital ICU)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria for myocardial infarction; 2. Meets the diagnostic criteria for True Cardialgia and Phlegm-Stasis Interlocking Syndrome; 3. No significant dietary preferences; 4. Has not used antibiotics, steroids, Chinese herbal preparations, microecological preparations, or probiotics such as yogurt in the past month; 5. Aged between 18 and 80 years; 6. The patient has signed an informed consent form and is willing to undergo the relevant examinations and treatments.
Exclusion criteria
Exclusion criteria: 1. Patients with cardiogenic shock, severe heart failure (NYHA class IV, or left ventricular ejection fraction =30%); 2. Severe liver or kidney dysfunction (serum alanine aminotransferase >3 times the upper limit of normal and/or serum creatinine level =265 umol/L); 3. Severe hematologic disorders, neurological or psychiatric disorders, malignant tumors; 4. Patients with concomitant organic lesions of the digestive system (such as peptic ulcer disease); 5. Currently using or requiring continuous use of drugs that may affect gastrointestinal function (antidiarrheals, antidepressants, anxiolytics, gut microbiota modulators, antibiotics, etc.); 6. History of severe allergic reactions to drugs used in the study or severe food allergies; 7. Pregnant or lactating women; 8. Participating in other studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left Ventricular End Diastolic Volume Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Left Ventricular End Systolic Volume Index ;Left Ventricular Ejection Fraction;Seattle Angina Questionnaire (SAQ);SF-36 Health Survey (Short Form 36);Traditional Chinese Medicine Syndrome Scale;Fecal Metagenomics;Blood and Urine Metabolomics; | — |
Countries
china
Contacts
Public ContactMaoshuai
The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed