digestive system disease
Conditions
Interventions
esketamine group:Induction of anesthesia: Esketamine 0.25mg/kg was slowly injected intravenously, then propofol was given 1.5-2mg /kg.
sunfentanil group:Induction of anesthesia: Sufentanil 0.1µg/kg was slowly injected intravenously, then propofol was given 1.5-2mg /kg.
Sponsors
the Affiliated Hospital of Qingdao University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1)patients undergoing EUS under sedation; 2)American Society of Anesthesiologists (ASA) grade I-?; 3)aged 18-75 years old; 4)Mallampati grade I-III.
Exclusion criteria
Exclusion criteria: 1)patients who may need to pump water into the esophagus and stomach in the examination process; 2)sleep apnea history; 3)evident difficult airway; 4)BMI>30; 5)Severe liver and kidney dysfunction; 6)patients who refused to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of respiratory depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of body movement;propofol induction dosage, supplemental times and total dosage;lowest SPO2;management of airway obstruction; | — |
Countries
China
Contacts
Public ContactZangong Zhou
the Affiliated Hospital of Qingdao University
Outcome results
None listed