underweight
Conditions
Interventions
Sponsors
Department of Anesthesiology, Affiliated Hospital of Sichuan North Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ? ASA class I-III, age 18-65 years. ? BMI <18.5 kg/m2 in underweight patients and between 18.5 kg/m2 -25 kg/m2 in normal weight patients. ? Not participating in other drug trials 2 weeks prior to the trial. ? No other factors affecting the metabolism of lidocaine. ? Able to read and understand the contents of the informed consent form and able to sign the informed consent form.
Exclusion criteria
Exclusion criteria: ? Allergic to lidocaine and narcotic drugs. ? Severe heart, brain and lung diseases. ? Severe hepatic and renal insufficiency impairment. ? Long-term use of cimetidine, beta-blockers and other drugs that affect the metabolism of lidocaine. ? Pregnant or lactating women. ? History of epilepsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma lidocaine concentration; | — |
Countries
China
Contacts
Public ContactTu Faping
Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed