Labor Analgesia
Conditions
Interventions
control group:Loading Dose: 12 - 15 ml of the mixture of 0.1% Ropivacaine Hydrochloride and 0.3 µg/ml Sufentanil Citrate.
Administration Method: 10 ml every 30 minutes for programmed intermittent epid
the study group:Loading Dose: 12 - 15 ml of the mixture of 0.06% Ropivacaine Hydrochloride and 0.3 µg/ml Sufentanil Citrate.
Administration Method: According to the progress of labor and the analgesic
Sponsors
Dalian Women and Children’s Medical Group
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1) ASA graded I-II primitives, 37 to 42 weeks gestation, single head position, natural labor; 2) Uterine dilation of 2 cm, digital pain assessment scale (NPRS) score > 4, age 18-40 years; 3) Prenatal examination No contraindications for vaginal delivery, no contraindications for intraspinal anesthesia, and no obstetric-related complications.
Exclusion criteria
Exclusion criteria: EP contraindications, gestational hypertension, pregnancy-related diseases (e.g., preeclampsia and gestational diabetes), body mass index (BMI) > 40 kg/m^2, biparietal diameter (BPD) = 100 mm, foetal head circumference (HC) = 350 mm, foetal weight = 4000 g and/or women who had taken opioids/sedatives within 4 h prior to EP.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to NPRS = 2;Total consumption of ropivacaine;Additional times of ropivacaine;Patient satisfaction;Duration from the Implementation of Labor Analgesia to the Latent Period (min);Duration of active period (min);Duration of second stage of labor (min);Total Amount of Oxytocin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausea, Vomiting;skin Itch;intrapartum fever;Forceps delivery;Postpartum hemorrhage;Incidence Rate of Urinary Retention 8 Hours after Delivery;Incidence Rate of Headache 48 Hours after Delivery;1-min Apgar score;5-min Apgar score;Bromage score;Observe the Feeling of Anal Distension in Parturients; | — |
Countries
China
Contacts
Public ContactMeihua Jin
Dalian Women and Children’s Medical Group
Outcome results
None listed