Acute liver failure in children
Conditions
Interventions
A retrospective study:None
Sponsors
The First Hospital of Jilin University
Eligibility
Sex/Gender
All
Age
28 Days to 16 Years
Inclusion criteria
Inclusion criteria: (1) Children diagnosed with acute liver failure who were admitted to the Pediatric Intensive Care Unit (PICU) of Jilin University First Hospital from January 2014 to May 1, 2024. The diagnostic criteria for pediatric acute liver failure are: ? Children without underlying chronic liver disease exhibit liver injury and develop severe liver dysfunction within 8 weeks of clinical liver disease onset; ? Coagulation disorders that cannot be corrected by vitamin K1 injection; ? Prothrombin time (PT) > 20s or International Normalized Ratio (INR) > 2.0, with no hepatic encephalopathy; or in cases of hepatic encephalopathy, PT > 15s or INR > 1.5. (2) Age range: 28 days < age = 16 years.
Exclusion criteria
Exclusion criteria: (1) Patients with incomplete information; (2) Those who give up treatment midway.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lactate/Albumin Ratio, LAR;Clinical outcomes at discharge; | — |
Countries
China
Contacts
Public ContactZhang Zhen
1 Xinmin Street, Chaoyang District, Changchun City, Jilin Province, Department of PICU, Children's Medical Center, the First Hospital of Jilin University
Outcome results
None listed