Cognitive impairment
Conditions
Interventions
experimental group:tDCS therapy
control group:sham stimulation
Sponsors
Affiliated Hospital of Hangzhou Normal University
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Over 60 years old; 2. Meet the possible diagnostic criteria for MCI or NIA-AA mild AD; 3. The Concise Mental State Examination Scale (MMSE) score is greater than 20 points; 4. Use a stable dose of therapeutic drugs for at least 3 months prior to tDCS treatment; 5. Passed tDCS safety screening, no metal implanted DBS electrode, no epilepsy and other neuropsychiatric diseases, no motor system diseases; 6. Pass MRI safety screening, have no history of head trauma and serious heart disease, and can complete MRI scan; 7. Sign the subject informed consent.
Exclusion criteria
Exclusion criteria: 1. There are obvious adverse reactions; 2. Actively quit the test; 3. Unable to judge the efficacy or incomplete data affecting the efficacy or safety judgment; 4. Head movement of all fMRI images, translational >3mm, rotational >3°
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function;fMRI; | — |
Countries
China
Contacts
Public ContactDanning Lou
Affiliated Hospital of Hangzhou Normal University
Outcome results
None listed