Ovarian hyperstimulation syndrome
Conditions
Interventions
Sponsors
Reproductive Hospital Affiliated to Jiangxi University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Normal healthy women: 1. Healthy women with regular menstruation (menstrual cycle is 21-35 days, menstrual period is 2-7 days). 2. Age 20-40 years old. 3. Those who voluntarily take the test and sign the informed consent form. Patients with ovarian hyperstimulation syndrome: (1) history of ovulation induction or ovarian stimulation; (2) have received injections that trigger oocyte maturation; (3) Abdominal distension/gastric distention, diarrhea/nausea/vomiting, ovarian enlargement, meeting the OHSS mild diagnostic criteria; (4) occurs during ovulation induction or within 10 days after triggering; (5) Age between 20~40 years old; (6) The enrolled patients were all in line with the diagnosis of infertility; (7) Voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: Normal healthy women: 1. Menstrual disorders in the past two months. 2. Those who are pregnant, lactating and lactating. 3. Have taken antibiotics, probiotics, contraceptives and other drugs in the past month. 4. Abnormal liver and kidney function. 5. Body weight: 18kg/m2> BMI>25kg/m2, accompanied by other organic diseases. 6. Those who are participating in other clinical trials. Patients with ovarian hyperstimulation syndrome: (1) abnormal liver and kidney function, with a history of hepatitis B. (2) Patients who have used antibiotics, probiotics and contraceptives in the past month. (3) Body weight: 18kg/m2> BMI>25kg/m2, accompanied by other organic diseases. (4) Malignant tumors. (5) Patients with unexplained vaginal bleeding who are not suitable for ovulation induction treatment. (6) Accompanied by other endocrine diseases. (7) Moderate to severe OHSS after egg retrieval. (8) OHSS occurs after pregnancy. (9) Those who are participating in other clinical investigations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptoms of self-awareness;Ovarian function;Stool high-throughput sequencing; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ovulation induction outcome;Blood hormone levels;Biochemical indicators; | — |
Countries
China
Contacts
Public ContactChen Weijun
Reproductive Hospital Affiliated to Jiangxi University of Traditional Chinese Medicine
Outcome results
None listed