painless abortion
Conditions
Interventions
Rimazolen benzenesulfonate (R group):Rimazolen benzenesulfonate
Propofol (P group):Propofol
Sponsors
Deyang People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1) Patients planning to undergo elective painless abortion; 2) Age 18-50 years old, female; 3) Body Mass Index (BMI): 18.5-28 kg/m2; 4) American Society of Anesthesiologists (ASA) classification: I-II; 5) Voluntarily participate in the experiment and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Individuals with a history of allergies to opioid drugs, benzodiazepines, propofol, flumazenil, or naloxone excipients; 2) Use beta blockers, anti anxiety drugs, and antidepressants; 3) Suspected abusers of narcotic analgesics or sedatives, as well as alcoholics; 4) Electrocardiogram prompt: heart rate100 beats/min or severe arrhythmia; 5) History of acute respiratory infection within 2 weeks without cure; 6) Individuals with a history of severe heart, brain, lung, liver, kidney, or metabolic diseases, as well as those with neurological and muscular disorders (such as myasthenia gravis) or mental illnesses; 7) Preoperative hypertension patients with systolic blood pressure>180 mmHg and/or diastolic blood pressure>110 mmHg, or hypotension patients<90/60 mmHg; 8) Individuals with a history of abnormal recovery from surgical anesthesia (delayed awakening, malignant hyperthermia); 9) Predict the possibility or occurrence of difficult airways, or improve the Mahalanobis classification III-IV level; 10) Other researchers believe that other subjects who are not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of successful operations;The occurrence of respiratory depression;Time indicator;body movement;Total dosage of medication;Number and dosage of intraoperative medication additions;Postoperative nausea and vomiting; | — |
Countries
China
Contacts
Public ContactXia Leqiang
Deyang People's Hospital
Outcome results
None listed