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Analysis of the influencing factors of chorioamnionitis and epidural analgesia induced fever during delivery and its impact on maternal and neonatal perinatal outcomes

Analysis of the influencing factors of chorioamnionitis and epidural analgesia induced fever during delivery and its impact on maternal and neonatal perinatal outcomes

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400090228
Enrollment
Unknown
Registered
2024-09-26
Start date
2024-10-01
Completion date
Unknown
Last updated
2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epidural analgesia for delivery, fever during labor, and fever caused by chorioamnionitis

Interventions

Chorioamniotis group (CAM):Perform placental pathological examination on pregnant women with fever during labor analgesia to determine whether chorioamnionitis has occurred
Epidural group:Perform placental pathological examination on pregnant women with fever during labor analgesia to determine whether chorioamnionitis has occurred

Sponsors

Shihezi People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 41 Years

Inclusion criteria

Inclusion criteria: (1) All cases had a gestational age greater than 37 weeks; (2) Epidural analgesia during labor resulted in fever (= 37.5 ?) (3). All cases in the CAM group were diagnosed with chorioamnionitis.

Exclusion criteria

Exclusion criteria: (1) Recently used antibiotics and/or glucocorticoids; (2) At admission, if the body temperature exceeds 37.5 ? or there are clinical symptoms of infection.

Design outcomes

Primary

MeasureTime frame
Pre pregnancy BMI, weight gain during pregnancy, oligohydramnios, amniotic fluid contamination, pregnancy complications, number of cervical examinations, duration of water breakthrough during delivery, water breakthrough>24 hours during delivery, delivery method, newborn weight;Results of total white blood cell count, percentage of neutrophils, hemoglobin, and C-reactive protein (CRP) in blood routine within 2 hours of fever;

Secondary

MeasureTime frame
Placental abruption rate, cesarean section rate, vaginal delivery rate, delivery bleeding volume, postpartum bleeding volume;The proportion of 1-minute and 5-minute Apgar<7 points, incidence of neonatal birth weight, neonatal jaundice, neonatal infection, and neonatal transfer to pediatrics;

Countries

china

Contacts

Public Contactcheyingjie

Shihezi People's Hospital

751564366@qq.com+86 182 9907 2057

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026