neurotrophic keratopathy
Conditions
Interventions
Interventions:Topical mecobalamin eye drops
Sponsors
Shandong Eye Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patient was diagnosed with neurotrophic keratitis by the investigator. Obtain written informed consent. Confocal microscopy shows evidence of reduced or absent corneal nerves in at least one corneal quadrant with hypocornea (based on the Cochet-Bonnet esthesiometer =4cm).
Exclusion criteria
Exclusion criteria: 1)The affected eye has any active eye infection (bacterial, viral, fungal or protozoan) or active eye inflammation that is not related to NK 2) Evidence of corneal ulceration, corneal dissolution, or perforation involving the posterior one-third of the corneal stroma in the affected eye.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Corneal sensitivity;Corneal nerve fibres; | — |
Secondary
| Measure | Time frame |
|---|---|
| best corrected visual acuity;Corneal fluorescein sodium staining;Intraocular pressure; | — |
Countries
China
Contacts
Public ContactWeiyun Shi
Shandong Eye Hospital
Outcome results
None listed