Osteoarthritis of the knee
Conditions
Interventions
APTT-HTO Routine rehabilitation group:Routine rehabilitation
APTT-HTO platelet-rich plasma group:Platelet-rich plasma intervention
APTT-HTO day surgery group:Rapid rehabilitation management process
APTT-HTO platelet-rich plasma + day surgery group:Enhanced recovery after surgery management process + intraoperative use of platelet-rich plasma
Sponsors
Affiliated Hospital of Guizhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Knee osteoarthritis (2) K/L scores are 2-4 (3) Combined with varus or valgus deformity of tibia (4) No local or systemic infection (5) The subject fully understands the content and risks of this experiment (6) Obtain the informed consent of the subject
Exclusion criteria
Exclusion criteria: (1) being over 90 years of age or under 18 years of age, or not having full capacity for civil conduct (2) HIV, hepatitis virus or syphilis virus infection or serological test positive (3) Rheumatoid arthritis or acquired knee deformity (4) Pregnant or lactating women (5) Tumor patients (patients with suspected tumor but not yet diagnosed, patients with confirmed tumor who will undergo surgery or radiotherapy or chemotherapy, patients with proximal tibial bone tumor) (6) Patients with immunodeficiency (including primary immunodeficiency and secondary immunodeficiency) (7) History of intraluminal drug injection three months ago (8) Participants who are currently participating in other clinical trials (9) Other concomitant diseases are not recommended for participants in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC score;Healing of osteotomy gap;Preoperative and postoperative changes of patellofemoral joint; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes of laboratory indexes before and after operation;Meniscal changes;Changes of anterior and posterior cruciate ligaments; | — |
Countries
China
Contacts
Public ContactYe chuan
Affiliated Hospital of Guizhou Medical University
Outcome results
None listed