PPROM
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Cases with a ruptured gestational week of 24-33+6 cycles to be preserved; (2) The drug regimen for infection prevention was penicillin G 4MIU q12h for patients who were not allergic to ß-lactams, first-generation cephalosporins (cefazolin 2g q12h, cefathiamidine 2g q12h) to prevent infections, and clindamycin 0.6g q12h for patients allergic to ß-lactams. (3) The pregnancy was eventually terminated in our hospital.
Exclusion criteria
Exclusion criteria: (1) Combination of serious pregnancy complications or complications that endanger the life of the mother and child, e.g., severe preeclampsia, liver disease, and severe anemia; (2) Admission has been clearly diagnosed with infection; (3) The patient has undergone multiple (>1) prophylaxis for infection due to PPROM.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adverse maternal and infant outcomes; | — |
Countries
China
Contacts
the First Affiliated Hospital of Army Medical University, PLA