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The effects of high-frequency rTMS combined with cognitive training on post-stroke cognitive impairment without dementia.

The effects of high-frequency rTMS combined with cognitive training on post-stroke cognitive impairment without dementia.

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400090135
Enrollment
Unknown
Registered
2024-09-24
Start date
2024-02-15
Completion date
Unknown
Last updated
2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-Stroke Cognitive Impairment

Interventions

Control group:group rTMS protocol: Stimulation site is the left dorsolateral prefrontal cortex, frequency is 10Hz, with 2 treatment sessions, each consisting of 600 pulses, with a 1-second interval, t
Experimental group:group rTMS protocol: Stimulation site is the left dorsolateral prefrontal cortex, frequency is 10Hz, with 2 treatment sessions, each consisting of 600 pulses, with a 1-second interv

Sponsors

Rehabilitation Center of the Second Hospital of Jiaxing City, Zhejiang Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria for Subjects, Exclusion Criteria, Steps for Selecting Subjects, and Methods for Allocating Subjects Diagnosed as PSCIND according to the "Expert Consensus on the Management of Post-Stroke Cognitive Impairment 2021" in 2021; 1. Patients who meet the diagnostic criteria for PSCIND and are confirmed to have cerebral infarction by CT or MRI. 2. First-onset, aged 30 to 70 years old, with unilateral cerebral infarction or cerebral hemorrhage. 3. Conscious upon admission, with stable vital signs and manifestations of cognitive impairment. 4. The course of the disease is between 2 weeks and 6 months. 5. All subjects are enrolled with the consent of the patients and their families, and an informed consent form is signed.

Exclusion criteria

Exclusion criteria: 1. Coma, severe cognitive impairment, severe aphasia, communication disorders, inability to cooperate with assessment and treatment, etc.; 2. Presence of cognitive impairment caused by other reasons (such as Alzheimer's disease); 3. History of previous craniocerebral trauma, other intracranial diseases or encephalitis; 4. History of previous depression, or presence of ethanol, drug abuse or dependence; 5. Patients or their families are uncooperative and do not agree to sign the informed consent form. 6. Age 70 years, course of disease 6 months; 7. Complicated with tumors, severe organ diseases, severe craniocerebral trauma and other diseases; 8. Patients with severe dementia and stroke.

Design outcomes

Primary

MeasureTime frame
MMSE( Minimum Mental State Examination);

Secondary

MeasureTime frame
Positive 300 wave;

Countries

China

Contacts

Public ContactZeng Ming

Rehabilitation Center of the Second Hospital of Jiaxing City, Zhejiang Province

Zengming2012828@163.com+86 150 6734 0759

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026