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Effectiveness and safety of magnesium sulfate sodium potassium oral solution and polyethylene glycol electrolyte solution for bowel preparation prior to colonoscopy: A nationwide multicenter cross-over randomized controlled trial

Effectiveness and safety of magnesium sulfate sodium potassium oral solution and polyethylene glycol electrolyte solution for bowel preparation prior to colonoscopy: A nationwide multicenter cross-over randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400090113
Enrollment
Unknown
Registered
2024-09-24
Start date
2024-11-30
Completion date
Unknown
Last updated
2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal polyp

Interventions

Group A:During the first colonoscopy, an oral solution of sodium potassium magnesium sulfate was taken as an intestinal preparation agent. Polyethylene glycol electrolyte powder was taken orally as an
Group B:During the first colonoscopy, polyethylene glycol electrolyte powder was taken orally as an intestinal preparation agent. An oral solution of magnesium sodium potassium sulfate was taken as an

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Endoscopic resection of colorectal polyps was performed in each research center; (2) Voluntarily participate in the test and sign informed consent.

Exclusion criteria

Exclusion criteria: (1) Allergic to the investigational drug and its ingredients; (2) Participating in other clinical trials or receiving special drug treatment; (3) Known or suspected gastrointestinal bleeding, gastrointestinal perforation, or gastrointestinal obstruction; (4) Ascites, suspected electrolyte abnormalities, or uncorrected dehydration; (5) Presence or high suspicion of colorectal cancer, inflammatory bowel disease, toxic colitis, or toxic megacolon; (6) Previous colorectal resection; (7) Known severe renal insufficiency, severe liver insufficiency, or severe congestive heart failure; (8) Patients with serious cardiovascular and cerebrovascular, metabolic, endocrine and other diseases cannot tolerate examination; (9) Pregnant or lactating women; (10) Constipation (frequency of defecation <3 times per week, difficult and laborious defecation, dry stool, small amount).

Design outcomes

Primary

MeasureTime frame
Qualification rate of intestinal preparation;

Secondary

MeasureTime frame
Security ;Acceptability;obedience;

Countries

China

Contacts

Public ContactBing Hu

West China Hospital of Sichuan University

hubingnj@163.com+86 189 8060 1278

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026