type 2 diabetes
Conditions
Interventions
Experimental group:The experimental group was given dagaglizin 10mg/ time, once /d, plus Xiaoke pill, the initial oral dose of Xiaoke pill was 5 pills/time, 3 times a day, and the adjustment was made
control group:Daglipzin 10mg/ time, once/day. Treatment for 12 weeks. The dose of daglizin remained unchanged during the period.
Sponsors
Shaowu Municiple Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: ? Meet the Western medicine diagnostic criteria for patients with type 2 diabetes mellitus combined with metabolic syndrome, and can be diagnosed with 3 or more of the following (B is necessary); A. Abdominal obesity (that is, central obesity) : waist circumference =90 cm for men and =85 cm for women. B. Hyperglycemia: fasting blood glucose = 6.1mmol /L or blood glucose = 7.8mmol /L 2 h after glucose loading and (or) have been diagnosed with diabetes and treated. C, hypertension: blood pressure =130/85 mmHg (1 mmHg=0.133 kPa) and/or have been recognized as hypertension and treated. D. Fasting triglyceride (TG) =1.70 mmol/L. E, fasting HDL-C< 1.04mmol /L. ? Consistent with Qi-Yin deficiency syndrome; Main symptoms: fatigue, dry throat, dry mouth, frequent urination, frequent urination at night. Secondary symptoms: easy hunger, thirst, shortness of breath, lazy talk, upset, hot hands and feet, hyperhidrosis, spontaneous sweating, night sweats, palpitation, insomnia, redness, constipation. Tongue and pulse: the tongue is red and less fluid, the fur is thin or the flower is peeled, and the pulse is weak or thin and string. ? Age 18-75 years old; ? Normal mental and conscious state; ? Sign informed consent.
Exclusion criteria
Exclusion criteria: ? History of serious infection or major surgery within the last 3 months; ? Pregnant or lactating women; ?Type 1 diabetes mellitus; ? dysfunction of vital organs (heart, brain, liver, kidney, etc.); ? There is a history of drug allergy or multiple food allergy; ? Patients with malignant tumor diseases, severe immune system diseases, cognitive dysfunction diseases, pathological obesity; ? Contraindications of Xiaoke pills and dagliagin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FPG;2h PG;HbA1c;TC;TG;LDL-C;HDL-C;SBP;DBP;CRP;PCT;UACR;MALB;Scr;BUN; | — |
Secondary
| Measure | Time frame |
|---|---|
| DSQL;TCM symptom score; | — |
Countries
China
Contacts
Public ContactMao Caifeng
Shaowu Municiple Hospital
Outcome results
None listed