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The observational study on the assessment of ablation effects and prognosis after radiofrequency ablation of lung nodules based on liquid biopsy with BDA-NGS

The observational study on the assessment of ablation effects and prognosis after radiofrequency ablation of lung nodules based on liquid biopsy with BDA-NGS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400090093
Enrollment
Unknown
Registered
2024-09-24
Start date
2024-09-30
Completion date
Unknown
Last updated
2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stage I-III non-small cell lung cancer (NSCLC).

Interventions

Stage I-III non-small cell lung cancer (NSCLC).:none

Sponsors

Beijing Chao-Yang Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Patients with lung cancer who visit Chaoyang Hospital; 2.Aged between 18 to 80 years old; 3.Willing to participate in the study and have signed the informed consent form; 4.Confirmed non-small cell lung cancer (NSCLC) patients who have undergone radiofrequency ablation treatment; 5.Clinical TNM staging is I-III (AJCC 8th Edition); 6.Have undergone CT examination in our hospital before treatment; 7.Blood samples have been collected and preserved before treatment

Exclusion criteria

Exclusion criteria: 1.Subjects with a history of other primary malignant tumors; subjects with other in situ cancers who have no evidence of disease and do not require treatment for 5 years or more can participate in the study; 2.Subjects with severe comorbidities, such as those with severe heart disease; 3.Subjects from whom insufficient tissue specimens cannot be obtained for genetic testing; 4.History of known Human Immunodeficiency Virus (HIV) disease or positive HIV viral tests; 5.Subjects who have undergone allogeneic transplantation (including xenogeneic heart valve transplantation); 6.Patients with undetected circulating tumor DNA (ctDNA); 7.Other conditions deemed unsuitable for participation in this study by the investigator.

Design outcomes

Primary

MeasureTime frame
Main lesion ablation rate;recurrence rate of 1 year;

Secondary

MeasureTime frame
Time to Progression;

Countries

China

Contacts

Public ContactHu Bin

Beijing Chao-Yang Hospital, Capital Medical University

hubin705@aliyun.com+86 139 0130 0750

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026