ovarian cancer
Conditions
Interventions
Neoadjuvant chemotherapy group :NA
non-neoadjuvant chemotherapy group:NA
Sponsors
Department of Anesthesiology, Affiliated Cancer Hospital of Nanjing Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1.Planned laparotomy for ovarian cancer resection under total intravenous anesthesia. 2.ASA classification II–III. 3.Age 18–64 years. 4.Body mass index 18.5–28 kg/m^2. 5.The patient or family member signed informed consent.
Exclusion criteria
Exclusion criteria: Intraoperative change in surgical approach. Intraoperative blood loss >15% of total blood volume. Severe intraoperative hemodynamic instability (blood pressure or heart rate deviating >30% from baseline). Surgery duration >6 hours or <2 hours. Missing clinical data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The average intraoperative consumption of remifentanil; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure (MAP) and heart rate (HR) ;The number of times vasopressors were used intraoperatively and the incidence of intraoperative adverse events (hypotension and bradycardia).;Time to extubation after admission to the anesthesia recovery room, time to spontaneous eye opening, incidence of nausea and vomiting in the recovery room, and number of analgesic doses administered.;Visual analogue scale (VAS) pain scores at rest and during activity on postoperative days 1, 2, and 3.;Use of rescue analgesics and pain medications by patients on postoperative days 1, 2, and 3.; Postoperative recovery details: time to first bowel movement, postoperative hospital stay duration, and total length of hospital stay.;The number of effective presses and the total number of presses on the patient-controlled intravenous analgesia (PCIA) pump postoperatively.;Number of times the remifentanil target concentration was adjusted based on the pain sensitivity index during surgery.; | — |
Countries
China
Contacts
Public ContactGao Rong
Department of Anesthesiology, Affiliated Cancer Hospital of Nanjing Medical University
Outcome results
None listed