primary aldosteronism
Conditions
Interventions
Experiment group:Operator completed the surgery using a computer-assisted surgical system
Control group:Operator completed the surgery without a computer-assisted surgical system
Sponsors
The Affiliated Hospital of Qingdao University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Hypertensive patients aged 18 to 70 years. 2.CT shows adrenal nodules or adenomas = 1 cm. 3.ARR = 30 (ng/dL)/(ng/mL/h) or ARR = 3.7 (ng/dL)/(mU/L). 4.At least one positive captopril suppression test. 5.Obtained informed consent.
Exclusion criteria
Exclusion criteria: 1.Renal hypertension, renovascular hypertension, and adrenal hypertension. 2.Patients who have recently experienced a state of stress, such as infection, trauma, and surgery, as well as those with a history of severe heart disease, liver and kidney dysfunction, and cardiovascular disease. 3.Patients eating corticosteroids, glycyrrhizin preparations, or oral contraceptives. 4.Patients with active malignant tumors. 5.Patients with a history of adrenalectomy or adrenal cortical insufficiency. 6.Patients with familial primary aldosteronism. 7.Patients unsuitable for surgery, such as those with heart failure classified as New York Heart Association (NYHA) class III or IV, severe anemia (hemoglobin < 60 g/L), stroke or acute coronary syndrome within the last three months, severe ascites and liver cirrhosis, and estimated glomerular filtration rate (eGFR) < 30(mL/min/1.73m²)..
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| aldosterone;cortisol; | — |
Secondary
| Measure | Time frame |
|---|---|
| operation time;contrast agent volume;Intraoperative access attempts; | — |
Countries
China
Contacts
Public Contactshufa li
The Affiliated Hospital of Qingdao University
Outcome results
None listed