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Study on the Therapeutic Effect of Lifei Xiaoji Pill on Lung Adenocarcinoma in the Early Stage of Ground Glass Nodule (Ia Stage) and Its Effect on Tumor Microenvironment

Study on the Therapeutic Effect of Lifei Xiaoji Pill on Lung Adenocarcinoma in the Early Stage of Ground Glass Nodule (Ia Stage) and Its Effect on Tumor Microenvironment

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400090077
Enrollment
Unknown
Registered
2024-09-24
Start date
2023-07-05
Completion date
Unknown
Last updated
2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Treatment group:On the basis of the treatment plan of western medicine, oral Lifei Xiaoji pills
Control group:Patients can use the treatment recommended by patients with "Ia stage NSCLC" in the Clinical diagnosis and treatment guidelines of Lung Cancer of Chinese Medical Association (2021 Editio

Sponsors

The First Affiliated Hospital of Henan University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) It met the diagnostic criteria of non-small cell lung cancer and was diagnosed by pathology, cytology and other related examinations. (2) Preoperative thin slice CT showed pure ground glass pulmonary nodules, the size of 10mm-30mm, intraoperative and postoperative pathology revealed adenocarcinoma, and the tumor stage (TNM) was Ia stage. (3) Aged 18 to 75 years old. (4) The estimated survival time is greater than 5 years. (5) Informed consent and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Patients who have undergone surgery. (2) Patients with severe dysfunction of heart, liver, lung, kidney and other important organs. (3) Mental illness and other patients who can not complete this study.

Design outcomes

Primary

MeasureTime frame
Quality of life measurement scale for lung cancer patients(FACT-L);TCM Symptoms and Syndromes;

Secondary

MeasureTime frame
Tumor markers CEA;Tumor markers CA211;Tumor markers squamous cell carcinoma antigen;Complete blood count: white blood cells;Complete blood count: haemoglobin; Complete blood count: Platelet;Liver function tests: ALT;Liver function tests: AST;Renal function tests: BUN;Renal function tests: Cr;

Countries

China

Contacts

Public ContactMingli Zhao

The First Affiliated Hospital of Henan University of Traditional Chinese Medicine

li3090221995@163.com+86 139 3715 9120

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026