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A controlled clinical study on the treatment of neonatal respiratory failure guided by cardiopulmonary ultrasound

A controlled clinical study on the treatment of neonatal respiratory failure guided by cardiopulmonary ultrasound

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400090064
Enrollment
Unknown
Registered
2024-09-23
Start date
2020-01-01
Completion date
Unknown
Last updated
2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal respiratory failure

Interventions

cardiopulmonary ultrasonography group:The positive end-respiratory pressure was adjusted under the guidance of cardiopulmonary ultrasound
traditional therapy group:The positive end-respiratory pressure was adjusted under the guidance of Chest radiograph

Sponsors

Hangzhou First People's Hospital affiliated to Westlake University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Infants with (1) a birth weight>1500 g and gestational age =32 week; and (2) postnatal respiratory failure. In neonates, respiratory failure was defined as admission to the NICU requiring respiratory support (including invasive mechanical ventilation (IMV) and/or noninvasive respiratory support).

Exclusion criteria

Exclusion criteria: Infants with (1) major congenital anomalies; (2) digestive tract malformations; and (3) neuromuscular diseases.

Design outcomes

Primary

MeasureTime frame
positive end-respiratory pressure;Number of cases of invasive ventilator ventilation;Number of cases of non-invasive ventilator ventilation;Non-invasive ventilator treatment failure cases; Noninvasive respiratory support time;Cases of pulmonary surfactant use;Time of invasive ventilator ventilation;

Secondary

MeasureTime frame
Total enteral feeding time;Length of stay;cases of air leakage syndrome;cases of intracranial hemorrhage;cases of bronchopulmonary dysplasia;cases of retinopathy prematurity;cases of necrotizing enterocolitis of the newborn;cases of death;cases of pulmonary hemorrhage;

Countries

China

Contacts

Public ContactZhiqun Zhang

Hangzhou First People's Hospital affiliated to Westlake University

Zhiqun.zhang@163.com+86 139 8945 3622

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026