macular degeneration, glaucoma
Conditions
Interventions
Test group:1.modulate the reponse of ipRGCs of human eyes by modifying the light spectrum of screen
2.modulate the reponse of the other photoreceptors of human eyes by modifying the light spectrum of screen
3.modulate the reponse of all photoreceptors of human eyes by modifying the luminance of screen. The test sequence is randomized for each subject.
Sponsors
University of Science and Technology of China (USTC), The first affliated hospital of USTC
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: healthy controls: 1) aged 18-90 years; 2) normal visual acuity or corrected visual acuity;3) normal color vision macular degeneration patients:1) aged 40-90 years; 2) diagnosed as dry macular degeneration, at least one eye has center visual acuity above 0.1 logMAR glaucoma patients:1) aged 40-75 years;2) diagnosed asglaucoma, at least one eye has center visual acuity above 0.5 logMAR
Exclusion criteria
Exclusion criteria: 1) eye diseases other than refractive error or the one for the targeting population (i.e., macular degeneration or glaucoma), and other diseases which can impair vision and visual perfomance significantly such as cognitive disorders; 2) intraocular surgery history within half year
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the size of visual crowding;visual adaption performance;the ability of orientation detetion and discrimination;attention performance; | — |
Secondary
| Measure | Time frame |
|---|---|
| other visual and cognitive performance; | — |
Countries
China
Contacts
Public ContactRong Liu
Department of life science and medicine, USTC
Outcome results
None listed