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Clinical study on the changes of cellular components and neuroplasticity in the process of bone tendon interface injury

Clinical study on the changes of cellular components and neuroplasticity in the process of bone tendon interface injury

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400090046
Enrollment
Unknown
Registered
2024-09-23
Start date
2023-08-27
Completion date
Unknown
Last updated
2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rotator cuff injury and ACL injury

Interventions

Rotator cuff injury group:NA
ACL injury group:NA

Sponsors

Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 70 Years

Inclusion criteria

Inclusion criteria: Rotator cuff injury group: To be eligible for this study, participants with rotator cuff injury must meet the following inclusion criteria: 1. X-ray and MRI showed rotator cuff injury; 2. Follow-up was completed with complete data. Anterior cruciate ligament injury group: 1. X-ray and MRI examination showed anterior cruciate ligament injury; 2. Physical examination: ADT test (+) or Lachman test (+); 3. Follow-up was completed with complete data.

Exclusion criteria

Exclusion criteria: Rotator cuff injury group: 1. Those who have metal grafts or are claustrophobic and cannot do nuclear magnetism; 2. Patients with cerebrovascular disease, central nervous system disease and psychiatric disease; 3. A prior history of shoulder surgery, including any degree of rotator cuff tear repair, any rotator cuff repair and revision, any proximal humeral fracture with rotator cuff tear; 4. Previous osteoarthritis; Metabolic diseases (diabetes, thyroid dysfunction, dyslipidemia, hypercholesterolemia, etc.); Autoimmune diseases (multiple sclerosis, muscular dystrophy, arthritis, lupus, etc.); Cancer; Connective tissue genetic disorders; Any illness resulting in impaired mobility or prolonged bedridden condition; 5. Long-term use of sedative hypnotic drugs. Anterior cruciate ligament injury group: 1. Those who have metal grafts or are claustrophobic and cannot do nuclear magnetism; 2. Patients with cerebrovascular disease, central nervous system disease and psychiatric disease; 3. Previous knee surgery history, including any ligament and tendon repair surgery; 4. Previous knee osteoarthritis; Metabolic diseases (diabetes, thyroid dysfunction, dyslipidemia, hypercholesterolemia, etc.); Autoimmune diseases (multiple sclerosis, muscular dystrophy, arthritis, lupus, etc.); Cancer; Connective tissue genetic disorders; Any medical condition that results in impaired mobility or prolonged bed rest; 5. Long-term use of sedative hypnotic drugs.

Design outcomes

Primary

MeasureTime frame
Proprioceptive measurement of shoulder and knee;Brain imaging indicators;

Secondary

MeasureTime frame
Constant shoulder score;Lysholm knee score scale;

Countries

China

Contacts

Public ContactHongbin Lv

Xiangya Hospital, Central South University

hongbinlu@qq.com+86 158 7488 9777

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026