Effect of low-dose alfentanil on half of the effective doses of remimazolam used successfully in induction of sedation under pediatric general anesthesia

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400090045

Enrollment

Unknown

Registered

2024-09-23

Start date

2024-09-23

Completion date

Unknown

Last updated

2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Alfentanil in combination with remimazolam group (Group A):Alfentanil 5ug/kg

Remimazolam group (Group R):Equal amount of saline

Eligibility

Sex/Gender

All

Age

3 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1. Age 3-12 years old 2. ASAI-II

Exclusion criteria

Exclusion criteria: 1. Inability to cooperate with intravenous induction 2. Difficult airway 3. May be allergic to medications related to this study 4. Mental nervous system development 5. History of preoperative sedative and analgesic use

Design outcomes

Primary

Measure	Time frame
The ED50 and ED95 of remimazolam;	—

Secondary

Measure	Time frame
Incidence of hiccups;Incidence of agitation;Incidence of injection pain;Incidence of hypotension;Incidence of bradycardia;	—

Countries

China

Contacts

Public ContactFanceng Ji

Weifang People's Hospital

jifanceng@163.com+86 135 6369 8838

Outcome results