Early Colorectal Cancer
Conditions
Interventions
Gold Standard:Histopathological diagnosis results
Index test:Physician A will use EUS alone to diagnose the remaining patients and record the diagnostic results of EUS
Physician B performed EUS examination on the patients submucosal injection of physiological saline and adrenaline without knowledge of Physician A's diagnosis, and recorded the diagnosis results.
Sponsors
Zhengzhou Center Hospital affiliated with Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (i) age between 18 and 85 years; (ii) early stage CRC with endoscopic JNET staging of Type2B; (iii) no severe cardiopulmonary dysfunction; (iv) normal coagulation function; (v) ability to afford the associated surgical costs (anesthesia and surgery); and (vi) good organ function.
Exclusion criteria
Exclusion criteria: (i) T2-T4 disease; (ii) exclusion of patients with severe intestinal disease; (iii) exclusion of patients diagnosed with advanced or metastatic CRC; (iv) patients with 75%-100% circumferential lesions of the intestine. ; (v) prior EUS, CT, or MRI suggestive of lymph node involvement or distant metastases; (vi) prior radiotherapy or chemotherapy; (vii) prior resection of colorectal lesions; (viii) severe chronic cardiac disease; (ix) pregnancy, breastfeeding, or planned pregnancy; and (x) other uncontrolled diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall accuracy of EUS diagnosis;Sensitivity of EUS diagnosis;Specificity of EUS diagnosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Risk factors affecting EUS diagnosis; | — |
Countries
China
Contacts
Public ContactKun-kun Li
Zhengzhou Center Hospital affiliated with Zhengzhou University
Outcome results
None listed