Colonoscopy Cleaning
Conditions
Interventions
Control group:drink 2L PEG the night before the procedure starting at 7 PM, drink 2L PEG at 7Am on the day of the procedure.
Test group1:take 290ug linaclotide at 7AM the day before the procedure, drink 2L PEG the night before the procedure starting at 7 PM, take 290ug linaclotide at 5AM on the day of the procedure, and
Test group2:take 290ug linaclotide at 7AM 2 days before the procedure, take 290ug linaclotide at 7AM the day before the procedure, drink 1L PEG the night before the procedure starting at 7 PM, take
Sponsors
Beijing Shijitan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for the study include patients undergoing EMR or ESD meet the following criteria: (1) age 18-70 years; (2) were able to comprehend the trial, sign a written informed consent, including consent a screening procedure to determine eligibility; (3) can communicate with the investigators well and follow verbal and written instructions; (4) take test drugs correctly according to the procedure; (5) undergo follow-up in accordance with the protocol.
Exclusion criteria
Exclusion criteria: Exclusion criteria for the study include patients meet one or more following criteria: (1) lack of an indication for full colonoscopy; (2) has a general contraindication to colonoscopy preparation, such as gastrointestinal obstruction, toxic megacolon, acute surgical abdomen including appendicitis, intestinal perforation and acute diverticulitis; (3) has one of the following diseases: electrolyte disturbances, severe diseases of the heart, liver or kidney; (4) history of any colonic surgery; (5) is taking or has taken linalotide, or is allergic to linalotide; (6)pregnant women; (7) lactating women; (8) are participating in other clinical trials or participated in other clinical trials within 60 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| comfort degree; | — |
Secondary
| Measure | Time frame |
|---|---|
| defecation frequency;Boston Bowel Preparation Scale score;caecal intubation rate;colonoscope insertion time and withdrawal time;adenoma detection rate; | — |
Countries
China
Contacts
Public ContactChunmei Guo
Beijing Shijitan Hospital, Capital Medical University
Outcome results
None listed