Clinical study of Changyanning and probiotics in antibiotic associated diarrhea

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400090014

Enrollment

Unknown

Registered

2024-09-23

Start date

2024-10-01

Completion date

Unknown

Last updated

2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

antibiotic associated diarrhea

Interventions

Experimental Group :Changyanning and probiotics

control group: probiotics

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Age range: 18-80 years old, clear consciousness, stable vital signs, answer questions correctly, willing to cooperate with treatment. (2) Recently or currently using antibiotics, experiencing diarrhea = 3 times/24 hours, may be accompanied by changes in stool properties, such as watery stools, bloody stools, mucous purulent stools, or the presence of plaque like pseudomembranes. (3) Voluntarily participate in this study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: (1) Infectious diarrhea, inflammatory bowel disease, intestinal tuberculosis and other intestinal diseases; (2) Accompanied by other serious underlying diseases, including severe pneumonia, acute heart failure, myocardial infarction, cerebral infarction, etc; (3) Pregnant or lactating women; (4) I am currently participating in other clinical drug trials.

Design outcomes

Primary

Measure	Time frame
Gastrointestinal symptom assessment;Gastrointestinal Quality of Life Index,GIQLI;	—

Secondary

Measure	Time frame
Inflammatory cytokine indicators;Adverse drug reactions;Intestinal flora analysis;	—

Countries

China

Contacts

Public ContactGuodong Li

the Affiliated Hospital of Hangzhou Normal University

3099174152@qq.com+86 138 1915 3755

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026