chronic metabolic diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1: Age 50-90, male or female. 2: Satisfies the definition of pre-debilitating or debilitating according to the Fried criteria. 3: Ability to be physically active.
Exclusion criteria
Exclusion criteria: 1: Currently on weight-loss medications or previous weight-loss surgery 2: End stage of serious diseases 3: Clear contraindications to exercise, including: severe systemic diseases, acute cardiovascular events, unrecovered severe infections, acute injuries to the musculoskeletal system Delete 4: Uncontrolled hypertension, diabetes mellitus (blood pressure =160 mmHg, blood glucose =11.1 mmol/L, glycated hemoglobin >10%) 5: Lack of independent mobility, including bed-ridden status, dependence on crutches, walkers, wheelchairs, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 6-minute walk test ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Other physical fitness indicators;Muscular Strength;Body compositon;vital capacity;Self-rating depression scale;Self-Rating Anxiety Scale;Pittsburgh sleep quality index;Quality of Life Short Form 12;The FRAIL Scale;blood pressure;blood sugar;blood fat;Insulin-like growth factor 1;score of sports Video; | — |
Countries
China
Contacts
Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union