Construction and validation of traditional Chinese and Western medicine management scheme for enteral nutrition feeding intolerance in patients with sepsis based on ACE star model

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400089991

Enrollment

Unknown

Registered

2024-09-22

Start date

2024-10-01

Completion date

Unknown

Last updated

2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

Observation group:1 screening (1.1.1 determination time: completed within 2 hours after admission. 1.1.2 screening tool: nrs2002 nutritional risk screening scale. 1.1.3 screening tool: acute gastroint

3-4 points, continue enteral nutrition.Enteral nutrition, slow down the original infusion rate by 50%, re evaluate the tolerance after 2 hours

= 5 points, suspend enteral nutrition, and make corresponding treatment.) 4 monitoring (4.1.1 monitor the gastric residual every 4 hours, and if possible, bedside gastric ultrasound can monitor the ga

In case of organ damage, it should be measured once every 1H.) 5 implementation (5.1.1 feeding

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: ? Age = 18 years old; ? Patients who meet the diagnostic criteria in the Chinese standard for the diagnosis and treatment of sepsis (2023 Edition) and whose SOFA score is 2-6 points; ? Sepsis patients who are ready to receive enteral nutrition support after admission to ICU; ? Complete case data; ? Obtain the consent of the patient/family member and sign the informed consent form; ? Septic patients with catheters.

Exclusion criteria

Exclusion criteria: ? Pregnant women; ? Patients with gastrointestinal related complications before admission to ICU, such as gastrointestinal bleeding, chronic diarrhea, intestinal obstruction, etc.; ? Sepsis patients who have begun to implement enteral nutrition; ? Patients with long-term use of hormones or immunosuppressive agents; ? End stage of various diseases, such as malignant tumor, cancer and other diseases; ? Acute infectious diseases; ? Septic shock patients; ? Severe metabolic disorders, such as diabetic ketoacidosis, hyperosmolar nonketotic diabetic coma; ? Patients with severe liver and kidney dysfunction and requiring dialysis.

Design outcomes

Primary

Measure	Time frame
Incidence of feeding intolerance;Nausea and abdominal pain during enteral nutrition;	—

Secondary

Measure	Time frame
7d target hot card compliance rate;Laboratory indicators;	—

Countries

China

Contacts

Public ContactYehong Wei

the Second Affiliated Hospital of Zhejiang Chinese Medical University

yehong8720@163.com+86 135 8817 8720

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026