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Remazolam besylate combined with dexmedetomidine for injection is used for ED50 and ED95 sedation for hallux valgus surgery

Remazolam besylate combined with dexmedetomidine for injection is used for ED50 and ED95 sedation for hallux valgus surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400089989
Enrollment
Unknown
Registered
2024-09-22
Start date
2024-09-22
Completion date
Unknown
Last updated
2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hallux valgus

Interventions

Observation group:None

Sponsors

South China University Affiliated South China Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: ?18 years old = age =60 years old, gender is not limited; ?ASA classification is ? to ?; ?12 times /min= respiratory rate =20 times /min; SpO2 suction air =93%; SBP=90mmHg; DBP=55mmHg; 55 times /min= heart rate =100 times /min; ?Be able to understand and voluntarily sign an informed consent form (ICF), be willing to comply with and expect to complete the test according to the requirements of the test protocol.

Exclusion criteria

Exclusion criteria: ? Patients with contraindications of deep sedation/general anesthesia or those with a history of sedation/anesthesia accidents; ?People who are allergic or contraindicated to benzodiazepines, dexmedetomidine, ropivacaine, lidocaine and their drug groups; ? Gastrointestinal history: history of gastrointestinal retention, active bleeding, gastroesophageal reflux or obstruction to assess the risk of reflux aspiration; ? Neurological history: craniocerebral injury, intracranial hypertension, brain aneurysm, cerebrovascular accident history; ? Psychiatric history: schizophrenia, mania, insanity, cognitive dysfunction history; ? Other conditions deemed unsuitable for inclusion by the investigator.

Design outcomes

Primary

MeasureTime frame
Successful sedation;

Countries

China

Contacts

Public ContactHuanhui Zhong

South China University Affiliated South China Hospital

zhhh21st@163.com+86 139 7475 0939

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026