macular edema with retinal vein occlusion
Conditions
Interventions
Experimental group:vitrectomy combined intravitreal anti-VEGF therapy and triamcinolone acetonide
Control group:intravitreal anti-VEGF therapy
Sponsors
Shanghai Jing'an District Shibei Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1) Patients with untreated macular edema secondary to retinal vein occlusion who visited the outpatient clinic of Ophthalmology at Shanghai Jing'an District Shibei Hospital between 1 September 2024 and 31 December 2027 were enrolled. 2) age = 18 years. 3) CMT (central macular thickness) >250um. 4) BCVA=0.5. 5)The diagnosis of RVO-ME is based on clinical examination findings, including flame-shaped retinal hemorrhage or dilated and tortuous retinal veins in one or more retinal quadrants, macular edema and subretinal fluid.
Exclusion criteria
Exclusion criteria: 1) Those with a previous history of vitrectomy. 2) Those with a previous history of retinal laser photocoagulation or intravitreal drug injection. 3) Eyes with diabetic retinopathy, age-related macular degeneration, choroidal neovascularization, macular hole, glaucoma, uveitis and high myopia (<-6.0D), amblyopia, and any other active ocular diseases. 4) corneal disease, vitreous hemorrhage, severe cataract and other severe refracting opacity affected examinees. 5) individuals with poor-quality SS-OCT images.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BCVA;Central macular thickness;Blood flow density; | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of intravitreal injections;The number of intraretinal hyperreflective foci;The disruption of the ellipsoid and ELM;The presence of intraretinal fluid and subretinal fluid ; | — |
Countries
China
Contacts
Public ContactJili Chen
Shanghai Jing'an District Shibei Hospital
Outcome results
None listed