Clinical Observation of Transcranial Direct Current Stimulation Combined with Rehabilitation Therapy on Functional Improvement in Knee Osteoarthritis

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400089958

Enrollment

Unknown

Registered

2024-09-20

Start date

2023-11-10

Completion date

Unknown

Last updated

2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

Experimental group:Conventional rehabilitation therapy + tDCS

Control group:Conventional rehabilitation therapy

Eligibility

Sex/Gender

All

Age

40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Meet the diagnostic criteria for KOA: Refer to the "Osteoarthritis Diagnosis and Treatment Guidelines" , with chronic pain as the main clinical symptom (VAS score = 3 points); 2.K-L grading of grade I-III, with no large loose bodies in the joint based on X-ray findings; 3.No relevant treatment received in the week prior to participation in this clinical trial, and no participation in other clinical trials in the past month; 4.Informed consent obtained from the patient and their family, and ability to comply with treatment and observation, as evidenced by signing the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Patients with knee joint pain not primarily due to KOA; 2.Patients with severe swelling in the knee joint, making assessment and exercise training difficult; 3.Patients with severe heart, brain, liver, kidney, hematologic disorders, or mental illness; 4.Patients with knee joint infection, open wounds, tumors, tuberculosis, or related rheumatologic immune system disorders; 5.Patients with a history of knee joint surgery or internal metallic implants; 6.Individuals with damaged skin at the site of stimulation or sensitivity to electrical currents.

Design outcomes

Primary

Measure	Time frame
Visual analogue scale (VAS);Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC);The three-dimensional gait;Surface electromyography of the lower extremities;The human body's balance indicators;Knee Injury and Osteoarthritis Outcome Score;	—

Secondary

Measure	Time frame
Lequesne Index;Short Form Health Survey SF-36;"Timed Up and Go" Test (TUGT);	—

Countries

China

Contacts

Public ContactJun Xing

The First Hospital of Hebei Medical University

56901734@hebmu.edu.cn+86 186 3388 9905

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026