surgery
Conditions
Interventions
A:The dose of dexmedetomidine is 0.6mcg/kg of actual body weight.
B:The dose of dexmedetomidine is 0.8mcg/kg of actual body weight.
C:The dose of dexmedetomidine is 1.0mcg/kg of actual body weight.
Sponsors
Zhongshan Hospital,Fudan University(Xiamen Branch)
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1 Patients undergoing elective surgery 2 Aged 18-60 3 ASA classification I-II 4 BMI between 18-30 5 Anesthesia method: general anesthesia with single-lumen endotracheal tube (7 or 7.5) 6 No major organ dysfunction, cardiopulmonary, liver and kidney function basically normal 7 Voluntary participation and signing of informed consent
Exclusion criteria
Exclusion criteria: ?Patients with a history of difficult endotracheal intubation ?Patients with a history of anesthetic allergy ?Patients with severe cardiovascular disease (New York Heart Association NYHA III-IV) or severe arrhythmia ?Patients receiving sedative or opioid medication ?Patients unable to fully understand and follow the trial process
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive reaction; | — |
Countries
China
Contacts
Public ContactChao Liang
Zhongshan Hospital,Fudan University(Xiamen Branch)
Outcome results
None listed