Adrenal tumor
Conditions
Interventions
Non-functional use of neostigmine and sodium gluconate (NFNS group):At PTC=1-2, neostigmine 20 µg/kg+ atropine 10 µg/kg was injected intravenously, and at TOF=1-2, Shugeng glucose sodium 2 mg/kg was i
Non-functional use of Shugeng sodium gluconate group (NFS):At PTC=1-2, intravenous injection of Shugeng glucose sodium 4 mg/kg.
Functional use of neostigmine and sodium gluconate (FNS group):At PTC=1-2, neostigmine 20 µg/kg+ atropine 10 µg/kg was injected intravenously, and at TOF=1-2, Shugeng glucose sodium 2 mg/kg was inject
Functional use of Shugeng glucose sodium group (FS group):At PTC=1-2, intravenous injection of Shugeng glucose sodium 4 mg/kg.
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1) Preoperative imaging examination of American Society of Anesthesiologists (ASA, Grade I ~ II) found adrenal space occupying lesions; 3) Adrenal tumor treated by laparoscopic general anesthesia; 4) There are pathological and morphological indexes after operation; 5) Complete clinical data. 6) Age > 18 years old.
Exclusion criteria
Exclusion criteria: 1) allergic to experimental drugs and contraindications; 2) Incomplete or lacking clinical data; 3) Patients with adrenal metastasis, (4) hand or upper limb disability, morbid obesity (body mass index = 30kg/m2), (5) preoperative use of antibiotics and other drugs that interfere with neuromuscular transmission, (6) refusal to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rocuronium dosage per unit time of 10kg body weight during operation (mg/10kg*h); | — |
Secondary
| Measure | Time frame |
|---|---|
| Time from the first dose of muscle relaxant to the recovery of TOFr to 0.7;Time from the first dose of muscle relaxant to TOFr recovery to 0.9;Time from the first dose of muscle relaxant to the removal of tracheal catheter; | — |
Countries
China
Contacts
Public ContactHong Ye
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed