Schizophrenia, bipolar disorder and major depressive disorder
Conditions
Interventions
schizophrenia group:none
Bipolar group:None
Depression group:None
Control group:None
Sponsors
Peking University Sixth Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-35 years old, gender unlimited, Han nationality; (2) Outpatient or inpatient patients; (3) The patients in different groups met the corresponding diagnostic criteria of DSM-5; (4) PANSS=70 in patients of schizophrenia;HAMD=17 in patients of bipolar disorder depressive episode;HAMD=17 in patients of major depressive disorder; (5) All subjects had junior high school education or above, and had no communication barrier; (6) non-blind and non-colorblind; (7) can cooperate to complete the multimodal eye functional imaging inspection; (8) signed informed consent.
Exclusion criteria
Exclusion criteria: 1: Patients with diabetes, high blood pressure, arteriosclerosis, thyroid disease, neurodegenerative diseases, etc 2: Patients with ocular diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Retinal nerve fiber layer thickness;Retinal vasculature diameter; | — |
Secondary
| Measure | Time frame |
|---|---|
| Retinal vascular blood oxygen saturation;Blood flow velocity;Blood oxygen metabolism parameter;pupil diameter;The reflectivity of the retina to different wavelengths of light;Eye movement velocity; | — |
Countries
China
Contacts
Public ContactShuzhe Zhou
Peking University Sixth Hospital
Outcome results
None listed