Postoperative pain in breast cancer
Conditions
Interventions
Bupivacaine liposome + bupivacaine hydrochloride group:Bupivacaine liposome 266mg + bupivacaine hydrochloride 112.5 mg
bupivacaine hydrochloride group:bupivacaine hydrochloride 112.5 mg
Sponsors
Affiliated Hospital of Yangzhou University
Eligibility
Sex/Gender
Female
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: Female patients undergoing elective modified radical mastectomy for breast cancer were selected. The inclusion criteria were American Society of Anesthesiologists physical status ?-?, aged 30-65 years, without major organ dysfunction.
Exclusion criteria
Exclusion criteria: BMI > 28 kg/m^2; Skin infection at the puncture site; Abnormal coagulation function; History of bupivacaine allergy; Chemotherapy was recently performed. Long-term oral analgesics; History of neurological disease; Those with communication difficulties.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute postoperative pain score after surgery;Quality of recovery at 72 hours (QOR-40 score); | — |
Secondary
| Measure | Time frame |
|---|---|
| Chronic postoperative pain after surgery;Tramadol consumption within 72 hours after surgery;Time of first rescue analgesia;adverse reaction; | — |
Countries
China
Contacts
Public ContactDawei Yang
Affiliated Hospital of Yangzhou University
Outcome results
None listed