hepatic encephalopathy
Conditions
Interventions
Control group:NA
Cirrhosis group:NA
Hepatic encephalopathy:NA
Sponsors
Sichuan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1: Inclusion criteria for the normal control group: (1) 80 years = age = 18 years; (2) not suffering from any underlying diseases, such as hypertension, diabetes, etc.; (3) not taking any medication for a long time, and drinking = 50 g/day; (4) not pregnant or in the breastfeeding period. 2: Inclusion criteria for patients with cirrhosis: (1) 80 years = age = 18 years; (2) those with a confirmed diagnosis of cirrhosis; and (3) those who were in the compensated stage of cirrhosis, with Child-Pugh class A, and who may have mild esophageal varices but no complications such as ascites or hepatic encephalopathy. 3: Inclusion criteria for patients with hepatic encephalopathy: (1) 80 years = age = 18 years; (2) patients with clinically diagnosed encephalopathy; and (3) no cerebral neurologic disease.
Exclusion criteria
Exclusion criteria: 1: Exclusion criteria for patients with cirrhosis: (1) those with comorbid metabolism-related disorders such as hypertension, diabetes mellitus, and thyroid disorders 2: those with a history of gastrointestinal bleeding in the last 2 weeks and with a hemoglobin concentration of <90 g/L 3: a score of <25 on the mini mental status examination(MMSE) 4: those who are pregnant or in the process of breastfeeding 5: those who are not able to cooperate with the study in terms of mental status, suffering from psychiatric disorders, lack of self-control, and inability to express themselves explicitly 6: those who are deemed by the investigators to be unsuitable for the clinical trial for other reasons 7: those who are unable to read or write the
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood untargeted metabolomics; | — |
Countries
China
Contacts
Public ContactPeng Li
Sichuan Provincial People's Hospital
Outcome results
None listed