Stroke
Conditions
Interventions
Experimental group:Formula "Shengqing Dangzhuo" combined with Meclofenoxate Hydrochloride
Control group:Meclofenoxate Hydrochloride
Sponsors
Shijiazhuang People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meets diagnostic criteria for ischemic stroke/hemorrhagic stroke. 2. In the recovery phase of ischemic stroke/hemorrhagic stroke. 3. Meets diagnostic criteria for post-stroke cognitive impairment: 1) Clear diagnosis of stroke. 2) Presence of cognitive impairment: Patients' self-reports, reports from informants, or clinical judgment by experienced clinicians indicate cognitive impairment occurring after stroke, and neuropsychological evidence confirms impairment in one or more cognitive domains or evidence of cognitive decline compared to previous status. 3) Temporal relationship between stroke and cognitive impairment: Occurs after stroke and persists for 3-6 months. 4. Age between 18 and 80 years. 5. Patient is conscious, vital signs are stable, compliance is good, and able to complete assessment scales. 6. Voluntary participation and signing of informed consent form.
Exclusion criteria
Exclusion criteria: 1. Individuals with cognitive impairment caused by conditions such as Alzheimer's disease, Parkinson's syndrome, brain tumors, metabolic or infectious diseases, or other etiologies. 2. Patients with severe underlying conditions such as severe hepatic or renal dysfunction, severe congestive heart failure, or significant coagulation abnormalities. 3. Patients unable to complete various assessment scales due to conditions such as aphasia. 4. Pregnant and lactating women. 5. Patients with a history of allergies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMSE ;MoCA;Intestinal Microbiota;Intestinal Metabolomics;CCS; | — |
Secondary
| Measure | Time frame |
|---|---|
| NIHSS;Fugl-meyer;CSBM; | — |
Countries
China
Contacts
Public ContactJianchao Xu
Shijiazhuang People's Hospital
Outcome results
None listed