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To explore the diagnostic markers and mechanism of chronic endometritis based on uterine microecology

To explore the diagnostic markers and mechanism of chronic endometritis based on uterine microecology

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400089903
Enrollment
Unknown
Registered
2024-09-19
Start date
2024-10-01
Completion date
Unknown
Last updated
2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic endometritis

Interventions

Gold Standard:Yes, gold standard: CD138+ cell count under fiberscopy
Index test:Eighty CE patients confirmed by hysteroscopy and tissue biopsy and 80 women undergoing hysteroscopy for benign diseases were included. Uterine swabs were collected for macrotranscriptomic a

Sponsors

Peking University Shenzhen Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Age 20-45 years old, premenopausal; Clinical diagnosis requires hysteroscopy and endometrial biopsy.

Exclusion criteria

Exclusion criteria: The presence of other serious gynecological diseases, such as uterine fibroids and ovarian cysts, may interfere with the evaluation of chronic endometritis; Having other serious chronic diseases, such as severe cardiovascular disease, kidney disease, etc., may affect the interpretation of the study results; Have had a hysterectomy or total hysterectomy, or any other procedure affecting the lining of the uterus; Currently undergoing clinical trials of other related drugs that may interfere with the accuracy of the study results; Women who are pregnant or breastfeeding, as these physiological states may affect the interpretation of the findings; Patients who have a severe allergic or intolerant reaction to a drug or treatment that may be used during the study; Have a severe mental or cognitive impairment that interferes with reasonable informed consent and research participation; Use of antibiotics or medication within 3 months at the time of visit; Participating in other research/projects.

Design outcomes

Primary

MeasureTime frame
Sensitivity to chronic endometritis was detected;

Countries

China

Contacts

Public ContactRuifang Wu

Peking University Shenzhen Hospital

wurf100@126.com+86 138 2743 3039

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026