bronchoscopy
Conditions
Interventions
the target-controlled infusion of alfentanil:the target-controlled infusion of alfentanil 35 ng/ml
the target-controlled infusion of sufentanil:the target-controlled infusion of sufentanil 0.2 ng/ml
the intravenous infusion of alfentanil group:One minute before propofol administration,intravenous injection of alfentanil 5 ug
/ml was administered
Sponsors
The Second Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-75 years old;BMI<28; (2) Meet the conditions for tracheoscopy. (3)No recent history of the use of sedative analgesic drugs. (4) No coagulation dysfunction,no recent history of taking aspirin and other anticoagulants.(5) Agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Drug allergy,allergy to the drugs used;(2) liver and kidney insufficiency;(3) hemodynamic instability;(4) American Society of Anesthesiologists (ASA) physical status classi?cation IV or V;(5)the baseline of SpO2<94%;(6)patients who cannot cooperate;(7)severe intraoperative bleeding;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative fluctuation of vital signs;Intraoperative coughing frequency; | — |
Secondary
| Measure | Time frame |
|---|---|
| the number of respiratory suppressions during surgery;wake-up time;Number and dosage of additional medications; | — |
Countries
China
Contacts
Public ContactDongnan Hou
The Second Hospital of Dalian Medical University
Outcome results
None listed