Perioperative sleep disorders
Conditions
Interventions
Propofol group (Propofol and remifentanil were used for intraoperative anesthesia maintenance):None
Sevoflurane group (Sevoflurane and remifentanil were used for intraoperative anesthesia maintenance):None
Sponsors
Shengjing Hospital of China Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=65 years old; 2. American Society of Anesthesiologists (ASA) Grade I ~ III; 3. The operation lasts 2-4 hours
Exclusion criteria
Exclusion criteria: 1. Have used sedatives, hypnotics, antipsychotics or antidepressants within the last 3 months, and have a history of mental and psychological disorders; 2. Patients with severe sleep disorder before surgery (PSQI=16); 3. Patients with low expected compliance (severe speech, hearing, vision, and cognitive impairment); Patients who underwent brain surgery and heart surgery within 4.1 years; 5. Patients who are expected to require night examination, intervention or clinical care after surgery; 6. Patients with other types of sleep disorders, such as apnea syndrome, restless leg syndrome, or periodic limb movements; 7. Patients who refused to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Athens Insomnia Scale Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Athens Insomnia Scale Score;Other sleep variables;Pittsburgh Sleep Quality Index, PSQI;Serum melatonin levels;Serum cortisol levels;Neuron-specific enolase levels in serum;Serum interleukin-6 levels;VisualAnalogueScale/Score,VAS;3D-Confusion Assessment Method (CAM) ; Quality of Recovery Scale-15;Medication interferes with sleep within 7 days after surgery;Postoperative emergency pain situation;Operation duration;Anesthesia duration;Other intraoperative drug use;Length of stay; | — |
Countries
China
Contacts
Public ContactJun Chai
Shengjing Hospital of China Medical University
Outcome results
None listed